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The results suggested that neither the change in A1c nor the change in body weight during the trial influenced the cardiovascular benefits of oral semaglutide

Activation of colonic GLP-1 receptors slows peristalsis (the muscle contractions that move stool), increases water absorption, and can decrease rectal sensitivity to the urge to defecate

In previous years we might have considered joining a gym or experimenting with a new diet, but now the weight-loss industry has a new string to its bow: diabetes treatments repurposed as weight-loss drugs

[1] [2] These effects result primarily from the medication's mechanism of slowing gastric motility

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