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doi:10.3390/nu7085311

According to Kannt & Pfenninger in Frontiers in Physiology , NAD is a critical coenzyme in mitochondrial energy metabolism, and strategies that preserve NAD have wide-ranging effects on health and performance (Kannt & Pfenninger, Frontiers in Physiology )

In the cells, the imbalance between production/elimination of free radicals (oxygen radicals and other reactive oxygen species (ROS)) leads to oxidative stress which causes detrimental damages to the macromolecules and vital structures in biological systems [9, 10]

While some users claim to see a slight difference without UV exposure, most say the results are faster and more visible when combined with sunlight or tanning beds