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Multiple factors may contribute to the variation of the usage of the drug

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These localized reactions may include redness, itching, swelling, bruising, or discomfort at the injection site

DPP4/CD26 transmembrane glycoprotein is not only expressed by various cells of the immune system, but also by epithelial and endothelial cells of systemic vasculature, by the endothelial cells of venules and capillaries, by the kidney, small intestine, lung, pancreas, spleen and heart, by the vascular smooth muscle cells, and by monocytes and hepatocytes and is soluble in the plasma [6, 7, 14]