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Intriguingly, consistent with our proposed hypothesis, positive correlations between the levels of T3 and the percentages of either HDCA or UDCA species were observed in this cohort of euthyroid human study participants (Fig
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Specifically, the GLP-1 co-secreted cousin PYY(1-36), agonist of the vasoconstrictive Y(1) receptor, is physiologically trimmed by DPP-IV to give rise to the appetite-suppressant, anti-diabetic and blood-brain barrier permeable PYY(3-36) agonist of Y(2) receptor (220)
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