Relative contraindications requiring careful consideration and enhanced medical supervision include history of pancreatitis, severe gastrointestinal disease including gastroparesis, diabetic retinopathy (requires ophthalmologic monitoring during therapy), severe kidney disease, history of suicidal ideation or severe depression, gallbladder disease or history of cholecystitis, and age under 18 years
Contraception is also recommended for women of child-bearing age using GLP-1s because of safety concerns raised by animal studies linking exposure of the medication during pregnancy to reduced foetal growth, slowed bone development and reduced maternal weight gain
10.1016/j.nbd.2018.04.016 76 MalkovA.IvanovA
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"This survey provides a helpful pulse on the HR community's need for a game plan around GLP-1 medications
