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During this process, ATP is broken down into adenosine diphosphate (ADP) and inorganic phosphate (P i )
Collectively, the results of this study suggest that NE and DA may have a protective effect against oxidative neurodegeneration through inhibition of protein disulfide isomerase and the subsequent activation of the MAPKsp53GADD45 oxidative cascade
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Over time, this contributes to weight gain, insulin resistance, and metabolic dysfunction
Regulated necrosis: disease relevance and therapeutic opportunities
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