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Cell multiplication While B12 is cofactor, methylfolate is the methyldonor in the above process
What is the refund policy if I experience adverse effects and need to discontinue
(May check a serum level 2 hours after the load.) This is not often done, but could be considered for patients with unusual pharmacokinetics (e.g., morbid obesity)
In women with PCOS, high concentrations of leptin have been reported to inhibit the expression of aromatase mRNA in granulosa cells, while the hyperandrogenic follicular environment in GCs was found to significantly reduce the expression of P450arom, which can convert androgens into estrogen, further increasing the levels of androgens and ultimately promoting follicular atresia (148150)
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