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Pharmacology Biochemistry and Behavior, 135 , 199-209

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10.1105/tpc.016055 47 HruzT.LauleO.SzaboG.WessendorpF.BleulerS.OertleL.et al

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It remains available only as a research compound

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A key differentiator of Mardrigals resmetirom is that in a pivotal Phase 3 trial, it achieved both primary endpoints of NASH resolution and reduction in fibrosis (MAESTRO-NASH), the two liver histological improvement endpoints the FDA has proposed as reasonably likely to predict clinical benefit

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