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Mast Cell Activation Syndrome (MCAS) is a highly frequent and disruptive comorbidity in patients living with Long COVID, ME/CFS, and dysautonomia
Despite providing important mechanistic insights, require further validation in randomized clinical trials (RCTs)
As shown in Figure 5E , DEG analysis revealed distinct gene expression profiles in MAC.2, with gene ontology pathway enrichment analysis indicating roles in bacterial response, response to lipopolysaccharides, response to molecules of bacterial origin, and cellular response to interleukin 1
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