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It was granted Orphan Drug designation by the European Medicines Agency (EMA) and the FDA last year as well as Rare Pediatric Disease designation by the FDA in 2023
Topical vitamin C in concentrations between 10-20% is generally safe for continuous use, while the sustainability and safety of prolonged glutathione use for cosmetic purposes requires more research
Lachowiez C, DiNardo CD, Takahashi K, Loghavi S, L-C X, Kadia TM, Daver N, Adeoti M, Short NJ, Sasaki K, Wang SA, Borthakur G, Issa GC, Maiti A, Alvarado Y, Pemmaraju N, Montalban-Bravo G, Masarova L, Yilmaz M, Jain N, Andreeff M , Garcia-Manero G, Kornblau SM, Ravandi F, Jabbour EJ, Konopleva M, MD, and Kantarjian H
Researchers tested it on mice, rats, rabbits and dogs without finding serious side-effects
