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Our recent work demonstrated that oxidized low-density lipoprotein (LDL) upregulates DPP-4 expression on macrophages via activation of Toll-like receptor 4 (TLR4)/TIR-domain-containing adapter-inducing interferon- (TRIF) and CD36 pathways [36]

It is produced within the body and found in high concentrations in several tissues

doi: 10.1016/j.eclinm.2023.101967 16 HuangLLuoYChenZ-LYangZ-YWuY

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