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MOTS-c improves insulin sensitivity, which compounds the glucose-lowering effect of these medications
As of April 2026, semaglutide (both the 0.25/0.5/1 mg Ozempic pens and the 0.25/0.5/1/1.7/2.4 mg Wegovy pens) remains in shortage, allowing compounding pharmacies to prepare semaglutide under Section 503A of the Federal Food, Drug, and Cosmetic Act
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However, Ozempic should NOT be used for weight loss, as it has not yet been authorized by the FDA for this purpose
If tiredness is due to low B12, treatment may help as levels improve
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