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Autophagosomes can efficiently dispose of IAPP small oligomers in p62-containing vacuoles to keep them from becoming toxic ( A seminal paper by Gurlo et al

Whalen KL, Lerchenfeldt SM, Giordano CR (Editors)

oralis have neuraminidase activity (Derrien et al., 2010)

[12] Absence of documented harm in small, short, unblinded series is not the same as demonstrated long-term safety, and the mechanistic rationale for these compounds promoting telomere maintenance is precisely the property that warrants careful oncological vigilance

The sulfur/selenium containing conjugates also exhibited H 2 O 2 (a commonly used analog of ROS) responsive drug release