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Muscle mass preservation is an important consideration given the risk of sarcopenic obesity: weight loss with GLP-1 RAs includes a lean mass component (approximately 25%-40% of total weight loss), though the clinical significance in MASLD patients without sarcopenia is uncertain
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The cell pellet was collected by centrifugation after overnight incubation at 28C, 180 rpm and stored at 80C until use
Caspase-1 also processes and promotes the maturation and release of IL-1 and IL-18, enhancing the local inflammatory response (Kovacs and Miao, 2017)
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