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In the Phase 2 obesity data the weight curve was still trending downward at 48 weeks, so a genuine plateau at a tolerated maintenance dose may simply reflect the body settling toward a new set point rather than the protocol failing
Minor increase in heart rate: Your heart rate may increase by 2 to 3 beats per minute, which is not harmful
J., Sheehan, S
If you had used 2 mL of water instead of 1.5, the concentration would be lower (2.5 mg/mL) and your highest dose would require 96 units, nearly the entire syringe
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