His medical history included only obesity, which was the reason for initiating semaglutide (Wegovy) therapy eight months earlier
Structure's Phase 2 trial enrolled people with obesity or who are overweight and have a weight-related complication like heart disease, randomizing 61 to receive aleniglipron and 12 to receive a placebo
Mild to moderate diarrhea is generally not dangerous and often resolves within 8-12 weeks as your body adapts
Colvin, which looked at birth records in Western Australia between 2002 and 2005, did not detect any adverse outcomes from the use of ondansetron in pregnancy but could not conclude that ondansetron is safe to use in pregnancy. While the study was too small to assess risks of individual birth defects (only 251 births associated with the drug out of almost 97,000 births total), the researchers found a six-fold increase in the risk for kidney malformations associated with ondansetron
The SURMOUNT-1 trial, the landmark study that led to tirzepatide FDA approval for weight management, provides the clearest data