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The data revealed that carnitine supplementation exhibited significant positive clinical effects in nearly 42% of patients, specifically targeting the profound cellular energy deficits that make upright posture intolerable
Peer review Peer review information Nature Reviews Cardiology thanks Luigi Fontana and the other, anonymous, reviewers for their contribution to the peer review of this work
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Obesity significantly elevates the risk of conditions such as type 2 diabetes, hypertension and cardiovascular disorders, creating stronger demand for treatments capable of producing sustained weight loss and improving overall metabolic health
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Real-time quantitative polymerase chain reaction Total RNA was extracted from cells using the Trizol reagent (Takara Bio Inc, Japan) according to the manufacturers instructions
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