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According to the same PMC/NIH review, topical GHK-Cu applied to thigh skin over 12 weeks improved collagen production in 70% of participants, compared with 50% for a vitamin C cream and 40% for retinoic acid in the same study a comparison that helped cement GHK-Cus reputation as a serious subject of dermatological research

Areas Studied in the Research Literature The published literature on GLP-1 SM and the broader GLP-1 receptor agonist class spans receptor pharmacology, peptide engineering, and mechanistic work in cell and animal models

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Not surface-level fixes