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Which reduces its practicality for medical injections, especially with multiple-use medications
The Annals of pharmacotherapy , 46 (2), 240247
doi: 10.1111/j.1365-2796.2011.02428.x 289 Cohen TervaertJWColarisMJvan der HulstRR
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A well-designed glutathione conjugation strategy considers substrate electrophilicity, the role of the cysteine thiol versus terminal amino or carboxyl groups, protection and deprotection needs, solvent and pH compatibility, oxidation risk, and the downstream analytical question the customer actually needs to answer
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