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Med 12 , 1727 (2022)
Both peptides are administered intranasally, simplifying the protocol for researchers already managing subcutaneous injections of other compounds
These signs may indicate cauda equina syndrome or another serious condition requiring urgent evaluation
Additionally, P9 induces interleukin-6 (IL-6) secretion from the intestine, which subsequently stimulates GLP-1 secretion by intestinal L-cells and pancreatic -cells, and also affects Icam2 mRNA expression, which suggests the normal expression of Icam-2 and the effects of P9 in glucose homeostasis may require IL-6 [160] (Fig
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