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Different mechanism, different risk profile
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Researchers weighing a blend against individual compounds should factor in study design flexibility as well as price a blend locks in a fixed ratio, while individual vials allow custom ratios
The Lancet (2021) This Phase 2 dose-finding trial randomized adults with overweight or obesity without diabetes to cagrilintide at doses from 0.3 to 4.5 mg weekly, placebo, or liraglutide 3.0 mg daily as an active comparator across 57 sites in 10 countries
