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These include: Nausea (very common, affecting more than 1 in 10 people) Diarrhoea (very common) Vomiting (common, affecting up to 1 in 10 people) Constipation (common) Abdominal pain (common) Dyspepsia (indigestion) These gastrointestinal symptoms typically occur during dose initiation or escalation and often diminish over time as the body adjusts to the medication

Practical factorssuch as insurance coverage, approved indication (type 2 diabetes vs obesity), drug availability, previous side effects, and co-existing health conditionsusually matter more than subtle mechanistic differences when deciding which medication to use and how aggressively to dose it

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According to the Cleveland Heart Lab, CoQ10 supplementation may reduce the risk for repeat heart attacks, lower blood pressure and may significantly lower levels of certain inflammatory biomarkers shown to increase the risk for cardiovascular disease