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A 2021 review in Frontiers in Pharmacology organised the wound-healing literature by tissue category, covering dermal, tendon, ligament, skeletal-muscle, osseous, peripheral-nerve, and vascular models (PMID 34267654)
A minimum of 8 weeks appears necessary to observe meaningful changes in chronic conditions, with 10 to 12 week cycles common
National Library of Medicine (US), MedlinePlus
These compounds have no FDA-approved indication and no billing code, and insurance does not cover them
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Combined with its ability to promote organised healing with less scar tissue formation, its becoming popular among chronic pain sufferers who havent found relief through conventional treatments
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