Pay in 4 interest-free payments of $5.61 Learn more
Ships within 48 hours · Estimated delivery Aug 26 - Aug 31
Atlanta, GA
Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery
T.SottasC
3.1 Riboflavin transporter deficiency Riboflavin transporter deficiency (RTD)historically termed BrownVialettoVan Laere or Fazio-Londe syndromeis a rare, early-onset motor neuron disease that couples the biochemistry of riboflavin with overt neurodegeneration ( SLC52A2 or SLC52A3 abrogate membrane uptake of riboflavin, precipitating secondary FMN/FAD depletion in metabolically demanding neurons and glia ( Mechanistic work in patient fibroblasts and iPSC-derived motor neurons confirms that transporter mutations collapse intracellular FMN/FAD pools, impair respiratory-chain flux and trigger neurite loss
10.1016/j.zemedi.2023.06.005
