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He compares these platforms to informal networks where people share experiences in real time
doi: 10.1038/s41572-022-00357-7 38 CaturegliPDe RemigisARoseNR
obliquus decreases FBG, improves intestinal barrier function, and restores the disrupted gut microbiota, characterizing upregulation of Ki-67, ZO-1, and MUC2 expression in the intestine, a restoration of the ratio of Firmicutes to Bacteroidetes, and enriched beneficial bacteria such as Akkermansia and Lactobacillus after the treatment in diabetic mice ( Ganoderma atrum polysaccharide (PGS) and white hyacinth bean polysaccharide (WHBP) ameliorated FBG and insulin resistance, as well as the levels of TC, TG, and LDL-C in T2DM rats
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These metabolites and small metabolic intermediates regulate intestinal immunometabolic homeostasis that includes energy metabolism, immune metabolism, and endocrine functions, and regulate the extent of mutualistic, commensal, and pathogenic relationships between the host and microbes 6,7
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