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doi:10.1016/j.bcp.2019.03.024 Yang L, Yang J, Pan T, Zhong X

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Cycle 8 weeks Weeks 14 300 mcg once daily Later weeks 500 mcg once daily during weeks 58 Review points Weeks 4 and 8 Evidence label Community standard Cycle 12 weeks Weeks 14 300 mcg once daily Later weeks 500 mcg once daily during weeks 512 Review points Weeks 4, 8, and 12 Evidence label Community standard Cycle 16 weeks Weeks 14 300 mcg once daily Later weeks 500 mcg once daily during weeks 516 Review points Every 4 weeks Evidence label Community standard No controlled human study has tested these subcutaneous schedules

The goal is to reduce exacerbations and improve lung function