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The experiment met the requirements of animal ethics with IRB no
It would take another 100 years before the central function performed by this lipid-rich sheathsaltatory conductionwas agreed upon
Moving from insulin to GLP-1 A patient on basal insulin whose Type 2 diabetes is relatively well controlled might transition to a GLP-1 agonist if they are gaining excessive weight on insulin, want to simplify their regimen, have developed cardiovascular risk factors that would benefit from GLP-1 protection, or have adequate remaining beta cell function
5 , 209ra151 (2013)
Gradually increase as tolerance builds
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