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Future: Dedicated NASH Phase 3 Trial Expected Timeline IF Retatrutide Approved for Obesity/Diabetes (2028): 2027-2028: Dedicated NASH Phase 3 trial begins Population: Biopsy-confirmed NASH with fibrosis (F1-F3) Primary endpoint: NASH resolution without worsening fibrosis Baseline and Week 72-96 liver biopsies Duration: 18-24 months minimum 2029-2030: Trial results published 2030-2031: FDA approval decision for NASH indication Why This Matters Current Reality: Only one FDA-approved medication exists for NASH resmetirom (Rezdiffra), approved March 2024
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9, Fox aired a controversial Hims & Hers Super Bowl commercial called Sick of the System which reached the 127 million viewers of the game and led to a 650 percent increase in website traffic for the company
The Swedish Medical Products Agency (Lkemedelsverket) and EMA require a prescription because these medicines: Require individual dose titration, incorrect dosing can produce severe adverse effects including nausea, ileus, and pancreatitis
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