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A second enzyme, NADPH-cytochrome P 450 oxidoreductase, transfers electrons to the CYP where it can, in the presence of O 2 , oxidize xenobiotic substrates, many of which are hydrophobic and dissolved in the ER
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Heavy metal associated health hazards: an interplay of oxidative stress and signal transduction
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In the posterior cortex, a reduction in DCFH levels was observed in the VPA+LipRSV group compared to the VPA group, suggesting that LipRSV treatment partially attenuated ROS production in this region
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