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If the patient does not tolerate the side effects at 2.4 mg, the doctor might prescribe 1.7 mg once weekly as the maintenance dose
The extreme appetite suppression could trigger restrictive patterns in susceptible individuals
In clinical trials, treatment with tirzepatide produced superior weight loss and glycemic control compared to GLP-1RAs 3,17 , suggesting that agonism at both the GIPR and GLP-1R is beneficial in humans with type 2 diabetes
A registered dietitian is the partner you need to get the best results possible from GLP-1s
Supplements with decades of human clinical trials still show response variability
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