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Subsequent 4 patients received lower doses of belatacept and tacrolimus without antimetabolite due to side effects of overimmunosuppression observed in the first patient from Cohort 2
Simultaneous targeting of NPC1 and VDAC1 by Itraconazole leads to synergistic inhibition of mTOR Signaling and Angiogenesis
The head-to-head trial results in December 2026 will clarify the picture
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