NAION risk Healio previously reported that semaglutide (Novo Nordisk) use was tied to a higher risk for nonarteritic anterior ischemic optic neuropathy (NAION), though past literature on this link has been inconsistent, which may be due to limited sample sizes and different study designs, Rong Xu, PhD, a professor of biomedical informatics at Case Western Reserve University, and colleagues wrote
The lawsuits were reinstated and remanded to Judge Battaglia for coordinated pretrial proceedings, which had been paused for about two years after the judge passed a motion for summary judgment filed by the drug makers in 2015, finding that the claims were preempted by federal law
The agency is also considering a Risk Evaluation and Mitigation Strategy program that would confirm the drugs potential risks do not outweigh the benefits
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This did not appear to be through changes to signal bias, as BETP at this dose did not affect cAMP or -arrestin-2 recruitment responses (Fig