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J Physiol.
Additionally, these medications slow gastric emptying, which prolongs the sensation of fullness after meals and reduces appetite through central nervous system effects on satiety centers in the hypothalamus
Patients with statin intolerance should first consider evidence-based alternatives like ezetimibe, bempedoic acid, PCSK9 inhibitors, or inclisiran before considering GLP-1 therapy primarily for lipid management
This is notably less pronounced than with GHRP-6 , which is famous for causing extreme, almost uncontrollable hunger
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