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Novel HBV biomarkers, including quantitative HBsAg, hepatitis B virus core-related antigen and HBV RNA are promising in predicting clinical phases, risks of disease progression and HBV functional cure
However, relying on these exceptions without legal guidance risks missing deadlines that could forever bar compensation claims
Overall, this trial was designed to precisely determine the dose-response relationship, efficacy, and safety of Cagrilintide compared with placebo and liraglutide, while employing advanced statistical methods to ensure reliable interpretation of treatment effects under both ideal and real-world adherence conditions
Jastreboff AM et al., Phase 2 retatrutide, NEJM 2023 (NEJMoa2301972, PMID 37366315) -24,2% at 48 weeks at the 12 mg level
