Diagnosis involves blood tests showing suppressed TSH with raised free T4 and/or T3, which supports hyperthyroidism
Intracellular glutathione concentrations vary by tissue typeliver and kidney maintain highest levels due to high detoxification demand
Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer
GLP-1 pills similarly work to lower blood sugar levels and curb appetite

Common Mounjaro side effects: feeling sick (nausea) diarrhoea vomiting constipation low blood sugar (if used with certain diabetes medications) indigestion stomach pain dizziness allergic reactions low blood pressure hair loss feeling tired bloating burping gas reflux or heartburn injection site reactions an increased level of some pancreatic enzymes as shown in blood tests (such as lipase) increased calcitonin levels Common Wegovy side effects: headache diarrhoea constipation nausea or vomiting (feeling or being sick) feeling weak or tired stomach pain upset stomach or indigestion dizziness burping gas bloating reflux or heartburn hair loss reactions at the injection site, like redness, swelling, or soreness gallstones inflamed stomach (gastritis), which can cause nausea, vomiting, and stomach ache low blood sugar in patients with diabetes, which is more likely if youre taking sulfonylurea or insulin a change in the way food or drink tastes a change in skin sensations (dysaesthesia) As the Wegovy injection and pill contain the same active ingredient, semaglutide, the side effects are the same
