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In isolated perfused rat pancreas, GLP-1 did not stimulate insulin release at glucose concentrations below 2.8 mM and could only promote insulin release when glucose concentrations were above 6.6 mM (Weir et al., 1989)
Petersburg Institute of Bioregulation and Gerontology in the late 1980s and 1990s as a synthetic analogue of the natural pineal-gland-extract complex epithalamin
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