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Protein helps prevent muscle loss and sarcopenia, while having a balancing effect on blood sugar and promoting satiety

It was originally isolated in 1977 from the cerebral venous blood of rabbits and has since been found to be present in small amounts in human brains and plasma, with higher concentrations later in the day.3 4 It, or a similar substance, is also present at higher concentrations in human breast milk.5 Because DSIP can cross the blood-brain barrier and is easily absorbed via the gut (unusual for a peptide), some researchers have hypothesized that it may facilitate post-feeding sleep tendencies among newborns, though it remains unclear whether DSIP truly has a hand in neonate sleep-wake cycles.4 5 6 Its mechanism of action is likewise unclear, but it may have something to do with endocrine regulation

Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis P

Elsewhere, on a lighter, but no less fascinating note, the brilliant Beth Abbit spent some time with Brian and the other Corrie superfans outside the studio gates in Trafford and found them delightful and weird in equal measure

Tirzepatide is newer and may have more limited access depending on location and insurance