Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-Like Signaling in C
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Insulin resistance, a known GH effect at supraphysiologic levels, compounds the glucose dysregulation already present in cirrhosis-related diabetes (hepatogenous diabetes affects approximately 30% of cirrhotic patients, per data in the Journal of Diabetes Research)
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[53] found that adult MIA mice had decreased GABAergic transmission from parvalbumin interneurons synapsing on pyramidal layer 2/3 of the medial prefrontal cortex