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Xtandiwhich is also approved for four other types of prostate canceris the first androgen receptor signaling inhibitor authorized to treat nmCSPC with biochemical recurrence at high risk for metastasis, according to the companies announcement

Journal of cutaneous medicine and surgery

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The alpha-amino nitrogen of the glycine, the deprotonated amide nitrogen of the peptide bond between glycine and histidine, and an imidazole nitrogen of the histidine side chain form the primary coordination sphere