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Correlation and mediation analysis We reported the correlation between the change in eGFR and change in body weight, systolic blood pressure and HbA 1c

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[1] Important safety considerations include the risk of pancreatitis (seek urgent medical attention for severe, persistent abdominal pain), gallbladder disease , dehydration leading to acute kidney injury (particularly with vomiting or diarrhoea), and potential worsening of diabetic retinopathy in those with pre-existing disease

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