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Anxiety is not listed among the common adverse reactions in the official Summary of Product Characteristics (SmPC) approved by the MHRA, nor does it feature prominently in the pivotal clinical trials that led to the medication's approval
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Both medications have stringent requirements for optimal absorption
Cooling the Itch via TRPM8
Thus, in patients with type 2 diabetes, combination incretin therapy is poised to provide better glycemic efficacy than treatment with a GLP-1 receptor agonist alone while maintaining a good side-effect profile with respect to avoiding hypoglycemia. As Healio previously reported, top-line data from SURPASS-4, the largest and longest trial of the program to date, also demonstrated that tirzepatide significantly reduced HbA1c and body weight compared with insulin glargine (Lantus, Sanofi) for adults with type 2 diabetes at high cardiovascular risk
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