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This move aims to address growing global demand and reduce supply constraints for GLP-1 receptor agonists used in obesity and diabetes treatment

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Hormonal status (i.e., pregnancy): Maternal toxicity can negatively affect the fetus

They share the broad mechanism class

In contrast, the glucose-lowering effect of T3 treatment could not be observed in the hypothyroid mice four hours after injection of a single dose of T3 (MMI + T3-4h mice), although these mice displayed very high levels of circulating T3 (Supplementary Fig