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Epitalon is primarily recognized for its role in activating telomerase, the enzyme responsible for maintaining telomere length, which is closely linked to cellular aging and longevity
Furthermore, thiazolidinedione derivatives (e.g., rosiglitazone and pioglitazone) demonstrate selective inhibition of ACSL4, consequently attenuating ferroptosis progression (Sheng et al., 2024)
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