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It can lead to a reduction in stomach acid and vitamin B12 absorption, which can cause additional health problems if left untreated

Semaglutide-associated depression: a report of two cases

Central nervous system effects may also play a role

Topiramate is an anticonvulsant licensed in the UK for epilepsy and migraine prevention, and although weight loss can occur as a side effect, it is not licensed for weight management and carries significant neurological, metabolic, and pregnancy-related risks