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An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

Methods Animals Male Swiss mice at 12 weeks of age (N = 40) were divided into 5 groups (n = 8 each) (Table 1) and kept in the vivarium of the State University of Montes Claros (UNIMONTES), Minas Gerais (MG), under standard temperature [22 2C], air humidity between 60 5%, 12h light/dark cycle, low sound levels (below 40 dB) with a balanced diet (50.3% carbohydrates, 41.9% protein and 7.8% fat (2.18 kcal/g Purina-Labine ) and filtered tap water ad libitum [38]

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