Together, these findings support an interaction framework in which prenatal stress is the principal driver of affective and social deficits, while THC modulates their magnitude and expression in a sex- and region-dependent manner, rather than producing uniform potentiation
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Older adults (60+) or those with obesity, metabolic syndrome, or poor baseline health may start at 250-300mcg given their typically reduced pituitary sensitivity and response
GSH, the most abundant antioxidant in the heart, plays a fundamental role in normalizing a redox homeostatic mechanism that was shifted toward oxidative or reductive stress