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Diuretic medications: amiloride (Midamor), triamterene (Dyrenium), spironolactone (Aldactone), etc
Drug delivery of macromolecules can also be afforded via this transport route, which relies on the electrostatic interactions between the surface of positively charged NPs (functionalized for instance with positive polymers, cationic lipids, albumin) and negative charges naturally present on endothelial plasma membrane (due to the presence of anionic proteoglycans) of the BBB (Poon and Garipy, 2007
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PMID: 22995213
Purity is assessed by HPLC to a specification of at least 99%, and identity is confirmed against the expected mass and the verified identifiers above (CAS 75921-69-6, PubChem CID 16197727, formula C78H111N21O19)
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