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This schedule is not arbitrary

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Certain habits and food choices can affect how well you tolerate the medication and achieve your goals

Clinical studies have demonstrated the feasibility of both approaches, with oral DCA being well-tolerated in patients with recurrent malignant brain tumors and Lonidamine showing modest efficacy in a Phase II study for recurrent glioma, thereby providing a clinical foundation for targeting glycolytic flux to suppress tumorigenic lactate generation [224, 225]