Sources of glutathione include broccoli, garlic, and avocado
Without a fully functioning PPP, intraplaque cellular death is likely increased and the ensuing atheroprotective process of efferocytosis may be dysfunctional
However, it is unclear exactly which isoform acts in cardiomyocytes and how it exerts its anti-ferroptosis effect, which requires further study
Foods and supplements that support glutathione production include nuts, legumes, beans, whey protein, milk thistle, eggs, beef, fish, poultry, flaxseed, spinach, and okra, along with cruciferous and allium vegetables such as broccoli, kale, onions, and garlic
When used in combination with cisplatin, it promoted cisplatin-induced cytotoxicity in vitro [61]