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Description

Loss of ER redox homeostasis can lead to ER stress and induction of the unfolded protein response (UPR) which, if severe enough will trigger cell death via the apoptotic pathway

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doi: 10.1056/NEJMoa2107519

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Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus

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Additionally, the evidence base for efficacy and safety specifically in BED populations remains limited

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